Hydrochloric Acid → 4-[7-(2-Morpholin-4-yl-2-oxo-ethoxy)-quinazolin-4-yl]-piperidine-1-carboxylic acid (4-pyrrolidin-1-yl-phenyl)-amide
Reaction equation
[C:1]([CH3:3])([CH3:4])([O:5][C:6](=[O:2])[N:8]1[CH2:9][CH2:10][CH:11]([c:14]2[n:15][cH:16][n:17][c:18]3[cH:19][c:20]([O:24][CH2:25][C:26](=[O:27])[N:28]4[CH2:29][CH2:30][O:31][CH2:32][CH2:33]4)[cH:21][cH:22][c:23]23)[CH2:12][CH2:13]1)[CH3:7].[ClH:34].[N+:35]([c:36]1[cH:37][cH:38][c:39]([O:40][C:41](=[O:42])[NH:46][c:47]2[cH:48][cH:49][c:50]([N:53]3[CH2:54][CH2:55][CH2:56][CH2:57]3)[cH:51][cH:52]2)[cH:43][cH:44]1)([O-:45])=[O:58]>>[O:5]=[C:6]([N:8]1[CH2:9][CH2:10][CH:11]([c:14]2[n:15][cH:16][n:17][c:18]3[cH:19][c:20]([O:24][CH2:25][C:26](=[O:27])[N:28]4[CH2:29][CH2:30][O:31][CH2:32][CH2:33]4)[cH:21][cH:22][c:23]23)[CH2:12][CH2:13]1)[NH:46][c:47]1[cH:48][cH:49][c:50]([N:53]2[CH2:54][CH2:55][CH2:56][CH2:57]2)[cH:51][cH:52]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-1970365cc496488c802230227bbcc425
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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