1,2-Dichloroethane → (3-Ethynylphenyl)-(6-methanesulfonylaminoquinazoline-4-yl)amine
Reaction equation
[CH3:27][S:28]([Cl:29])(=[O:30])=[O:31].[Cl:32][CH2:33][CH2:34][Cl:35].[NH2:1][c:2]1[cH:3][c:4]2[c:5]([NH:12][c:13]3[cH:14][c:15]([C:19]#[CH:20])[cH:16][cH:17][cH:18]3)[n:6][cH:7][n:8][c:9]2[cH:10][cH:11]1.[cH:21]1[cH:22][cH:23][n:24][cH:25][cH:26]1>>[NH:1]([c:2]1[cH:3][c:4]2[c:5]([NH:12][c:13]3[cH:14][c:15]([C:19]#[CH:20])[cH:16][cH:17][cH:18]3)[n:6][cH:7][n:8][c:9]2[cH:10][cH:11]1)[S:28]([CH3:27])(=[O:30])=[O:31]Participants
5
Sources & evidence
- ORD record
- ord-a025b40835814e89bce58cf915ec8901
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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