Acetone → tert-Butyl 3-(bromomethyl)pyrrolidine-1-carboxylate

HRID 2136498Notes

Reaction equation

HRID 2136498 reaction equation
[Br-:22].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([CH2:13][O:14][S:15]([C:16]([F:17])([F:18])[F:19])(=[O:20])=[O:21])[CH2:11][CH2:12]1.[CH3:24][C:25](=[O:26])[CH3:27].[Li+:23]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([CH2:13][Br:22])[CH2:11][CH2:12]1

Participants

5

Reactant 4

HCID 180AcetoneHCID 259Bromide ionHCID 28486Lithium ionHCID 53385508tert-Butyl 3-((((trifluoromethyl)sulfonyl)oxy)methyl)pyrrolidine-1-carboxylate

Product 1

HCID 24730280tert-Butyl 3-(bromomethyl)pyrrolidine-1-carboxylate

Sources & evidence

ORD record
ord-956dadc701474e34bf7bb70472c1233b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

Loading…