Dimethylformamide → 2-Chloro-7,7-difluoro-5-methyl-9-(2-phenoxy-ethyl)-5,7,8,9-tetrahydro-pyrimido[4,5-b][1,4]diazepin-6-one
Reaction equation
[C:17](=[O:18])([O-:19])[O-:20].[CH3:33][N:34]([CH3:35])[CH:36]=[O:37].[Cl:1][c:2]1[n:3][cH:4][c:5]2[c:6]([n:16]1)[NH:7][CH2:8][C:9]([F:14])([F:15])[C:10](=[O:13])[N:11]2[CH3:12].[Cs+:21].[Cs+:22].[I:23][CH2:24][CH2:25][O:26][c:27]1[cH:28][cH:29][cH:30][cH:31][cH:32]1>>[Cl:1][c:2]1[n:3][cH:4][c:5]2[c:6]([n:16]1)[N:7]([CH2:24][CH2:25][O:26][c:27]1[cH:28][cH:29][cH:30][cH:31][cH:32]1)[CH2:8][C:9]([F:14])([F:15])[C:10](=[O:13])[N:11]2[CH3:12]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-bf174140cea44afdb7465d9438e9421c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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