Dichloromethane → [8-Chloro-6-(2-fluorophenyl)-4H-imidazo[1,5-a][1,4]benzodiazepin-1-yl]methyl acetate

HRID 2137094Notes

Reaction equation

HRID 2137094 reaction equation
[C:1]([CH3:2])(=[O:3])[O:4][CH2:5][c:6]1[n:7][cH:8][c:9]2[n:10]1-[c:11]1[c:12]([cH:24][c:25]([Cl:28])[cH:26][cH:27]1)[C:13]([c:17]1[c:18]([F:23])[cH:19][cH:20][cH:21][cH:22]1)=[N+:14]([O-:16])[CH2:15]2.[CH2:33]([Cl:34])[Cl:35].[Cl:29][P:30]([Cl:31])[Cl:32]>>[C:1]([CH3:2])(=[O:3])[O:4][CH2:5][c:6]1[n:7][cH:8][c:9]2[n:10]1-[c:11]1[c:12]([cH:24][c:25]([Cl:28])[cH:26][cH:27]1)[C:13]([c:17]1[c:18]([F:23])[cH:19][cH:20][cH:21][cH:22]1)=[N:14][CH2:15]2

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 24387Phosphorus trichlorideHCID 121759821-Acetoxymethyl-8-chloro-6-(2-fluorophenyl)-4H-imidazo[1,5-a][1,4]benzodiazepine 5-Oxide

Product 1

HCID 15563271[8-Chloro-6-(2-fluorophenyl)-4H-imidazo[1,5-a][1,4]benzodiazepin-1-yl]methyl acetate

Sources & evidence

ORD record
ord-ae3057eac42245f4a483af9982a5ea9e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

Loading…