Dichloromethane → tert-Butyl (6-cyano-2-oxo-2,3-dihydrobenzimidazol-1-yl)phenylacetate

HRID 2137381Notes

Reaction equation

HRID 2137381 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[CH:8]([n:9]1[c:10](=[O:27])[n:11]([C:20]([O:21][C:22]([CH3:23])([CH3:24])[CH3:25])=[O:26])[c:12]2[c:13]1[cH:14][c:15]([C:18]#[N:19])[cH:16][cH:17]2)[c:28]1[cH:29][cH:30][cH:31][cH:32][cH:33]1.[Cl:41][CH2:42][Cl:43].[OH:34][C:35]([C:36]([F:37])([F:38])[F:39])=[O:40]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[CH:8]([n:9]1[c:10](=[O:27])[nH:11][c:12]2[c:13]1[cH:14][c:15]([C:18]#[N:19])[cH:16][cH:17]2)[c:28]1[cH:29][cH:30][cH:31][cH:32][cH:33]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 66755109tert-Butyl 3-(tert-butoxycarbonylphenylmethyl)-5-cyano-2-oxo-2,3-dihydro-benzimidazole-1-carboxylate

Product 1

HCID 86642497tert-Butyl (6-cyano-2-oxo-2,3-dihydrobenzimidazol-1-yl)phenylacetate

Sources & evidence

ORD record
ord-832c0dec1e3a4554a862286374d052f3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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