Methanol → (E)-methyl 5-(hydroxymethyl)-2-(8-(3-((2-(trimethylsilyl)ethoxy)methyl)benzo[d]thiazol-2(3H)-ylidenecarbamoyl)-3,4-dihydroisoquinolin-2(1H)-yl)thiazole-4-carboxylate
Reaction equation
[BH4-:42].[CH2:46]1[O:47][CH2:48][CH2:49][CH2:50]1.[CH3:44][OH:45].[CH:1](=[O:2])[c:3]1[c:4]([C:38](=[O:39])[O:40][CH3:41])[n:5][c:6]([N:8]2[CH2:9][c:10]3[c:11]([C:18]([N:19]=[c:20]4[s:21][c:22]5[c:23]([n:24]4[CH2:25][O:26][CH2:27][CH2:28][Si:29]([CH3:30])([CH3:31])[CH3:32])[cH:33][cH:34][cH:35][cH:36]5)=[O:37])[cH:12][cH:13][cH:14][c:15]3[CH2:16][CH2:17]2)[s:7]1.[Na+:43]>>[CH2:1]([OH:2])[c:3]1[c:4]([C:38](=[O:39])[O:40][CH3:41])[n:5][c:6]([N:8]2[CH2:9][c:10]3[c:11]([C:18]([N:19]=[c:20]4[s:21][c:22]5[c:23]([n:24]4[CH2:25][O:26][CH2:27][CH2:28][Si:29]([CH3:30])([CH3:31])[CH3:32])[cH:33][cH:34][cH:35][cH:36]5)=[O:37])[cH:12][cH:13][cH:14][c:15]3[CH2:16][CH2:17]2)[s:7]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-941426d1a76146bea64950a63ffa6d9d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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