Trifluoroacetic acid → Tert-butyl 4-hydroxypiperidine-1-carboxylate

HRID 2137498Notes

Reaction equation

HRID 2137498 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([O:14][c:15]2[cH:16][cH:17][cH:18][c:19]([Cl:20])[cH:21]2)[CH2:12][CH2:13]1.[OH:22][C:23]([C:24]([F:25])([F:26])[F:27])=[O:28]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([OH:14])[CH2:12][CH2:13]1

Participants

3

Reactant 2

HCID 6422Trifluoroacetic acidHCID 68536956HCID 68536956, compound

Product 1

HCID 643502Tert-butyl 4-hydroxypiperidine-1-carboxylate

Sources & evidence

ORD record
ord-0285ced2d327416f8a2c4fa3d152359d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

Loading…