Hydrochloric Acid → (3RS, 4SR)-1-benzyl-3-(4-chloro-phenyl)-piperidine-4-carboxylic acid methyl ester

HRID 2137718Notes

Reaction equation

HRID 2137718 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH:10]([c:17]2[cH:18][cH:19][c:20]([Cl:23])[cH:21][cH:22]2)[CH:11]([C:14](=[O:15])[OH:16])[CH2:12][CH2:13]1.[CH3:25][OH:26].[CH3:27][OH:28].[ClH:24]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH:10]([c:17]2[cH:18][cH:19][c:20]([Cl:23])[cH:21][cH:22]2)[CH:11]([C:14]([O:15][CH3:25])=[O:16])[CH2:12][CH2:13]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 887Methanol2×HCID 68479302(3RS,4SR)-1-benzyl-3-(4-chloro-phenyl)-piperidine-4-carboxylic acid

Product 1

HCID 68517588(3RS, 4SR)-1-benzyl-3-(4-chloro-phenyl)-piperidine-4-carboxylic acid methyl ester

Sources & evidence

ORD record
ord-f6a71c6ffec346f9a7b9eb5b45b12c5c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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