Diisopropylamine → methyl 3-[2-n-butyl-1-(2-chlorophenyl)methyl-1H-imidazol-5-yl]-3-hydroxy-2-(2-thienyl)methyl-propanoate
Reaction equation
[CH2:24]([CH2:25][CH2:26][CH3:27])[c:28]1[n:29]([CH2:35][c:36]2[c:37]([Cl:42])[cH:38][cH:39][cH:40][cH:41]2)[c:30]([CH:33]=[O:34])[cH:31][n:32]1.[CH2:8]([Li:9])[CH2:10][CH2:11][CH3:12].[CH:1]([NH:2][CH:3]([CH3:4])[CH3:5])([CH3:6])[CH3:7].[O:43]1[CH2:44][CH2:45][CH2:46][CH2:47]1.[s:13]1[c:14]([CH2:18][CH2:19][C:20](=[O:21])[O:22][CH3:23])[cH:15][cH:16][cH:17]1>>[s:13]1[c:14]([CH2:18][CH:19]([C:20](=[O:21])[O:22][CH3:23])[CH:33]([c:30]2[n:29]([CH2:35][c:36]3[c:37]([Cl:42])[cH:38][cH:39][cH:40][cH:41]3)[c:28]([CH2:24][CH2:25][CH2:26][CH3:27])[n:32][cH:31]2)[OH:34])[cH:15][cH:16][cH:17]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-4f2ffd9520c243838de6b5952a980526
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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