Methanol → tert-Butyl 4-(3-hydroxyphenyl)piperazine-1-carboxylate

HRID 2137822Notes

Reaction equation

HRID 2137822 reaction equation
[C:34]([O:35][CH2:36][CH3:37])(=[O:38])[CH3:39].[CH3:30][OH:31].[CH3:32][OH:33].[H:28][H:29].[OH-:40].[OH-:42].[Pd+2:41].[c:1]1([CH2:2][O:8][c:9]2[cH:10][c:11]([N:15]3[CH2:16][CH2:17][N:18]([C:21](=[O:22])[O:23][C:24]([CH3:25])([CH3:26])[CH3:27])[CH2:19][CH2:20]3)[cH:12][cH:13][cH:14]2)[cH:3][cH:4][cH:5][cH:6][cH:7]1>>[OH:8][c:9]1[cH:10][c:11]([N:15]2[CH2:16][CH2:17][N:18]([C:21](=[O:22])[O:23][C:24]([CH3:25])([CH3:26])[CH3:27])[CH2:19][CH2:20]2)[cH:12][cH:13][cH:14]1

Participants

7

Reactant 6

HCID 887Methanol2×HCID 961Hydroxide2×HCID 8857Ethyl AcetateHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 18669100HCID 18669100, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 18669061tert-Butyl 4-(3-hydroxyphenyl)piperazine-1-carboxylate

Sources & evidence

ORD record
ord-86828b798b534baf9c5702290c9a4061
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

Loading…