N-methyl-2-pyrrolidone → N-(5-Bromo-4-(1-methylpiperidin-4-ylamino)pyridin-2-yl)pivalamide
Reaction equation
[Br:1][c:2]1[c:3]([Cl:15])[cH:4][c:5]([NH:8][C:9]([C:10]([CH3:11])([CH3:12])[CH3:13])=[O:14])[n:6][cH:7]1.[CH3:16][N:17]1[CH2:18][CH2:19][CH:20]([NH2:23])[CH2:21][CH2:22]1.[CH3:24][N:25]1[CH2:26][CH2:27][CH2:28][C:29]1=[O:30]>>[Br:1][c:2]1[c:3]([NH:23][CH:20]2[CH2:19][CH2:18][N:17]([CH3:16])[CH2:22][CH2:21]2)[cH:4][c:5]([NH:8][C:9]([C:10]([CH3:11])([CH3:12])[CH3:13])=[O:14])[n:6][cH:7]1Participants
4
Sources & evidence
- ORD record
- ord-4cd2ef292761411695adf8e50a681a58
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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