Dichloromethane → (6-(1-(Benzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)pyridin-3-yl)(2-methoxyphenyl)methyl methanesulfonate

HRID 2138442Notes

Reaction equation

HRID 2138442 reaction equation
[CH3:1][S:2]([Cl:3])(=[O:4])=[O:5].[CH:37]([N:38]([CH2:39][CH3:40])[CH:41]([CH3:42])[CH3:43])([CH3:44])[CH3:45].[Cl:46][CH2:47][Cl:48].[OH:6][CH:7]([c:8]1[cH:9][cH:10][c:11]([NH:14][C:15](=[O:16])[C:17]2([c:20]3[cH:21][c:22]4[c:23]([cH:27][cH:28]3)[O:24][CH2:25][O:26]4)[CH2:18][CH2:19]2)[n:12][cH:13]1)[c:29]1[c:30]([O:35][CH3:36])[cH:31][cH:32][cH:33][cH:34]1>>[CH3:1][S:2](=[O:4])(=[O:5])[O:6][CH:7]([c:8]1[cH:9][cH:10][c:11]([NH:14][C:15](=[O:16])[C:17]2([c:20]3[cH:21][c:22]4[c:23]([cH:27][cH:28]3)[O:24][CH2:25][O:26]4)[CH2:18][CH2:19]2)[n:12][cH:13]1)[c:29]1[c:30]([O:35][CH3:36])[cH:31][cH:32][cH:33][cH:34]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 31297Methanesulfonyl chlorideHCID 81531DiisopropylethylamineHCID 442365991-(benzo[d][1,3]dioxol-5-yl)-N-(5-(hydroxy(2-methoxyphenyl)methyl)pyridin-2-yl)cyclopropanecarboxamide

Product 1

HCID 57895126(6-(1-(Benzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)pyridin-3-yl)(2-methoxyphenyl)methyl methanesulfonate

Sources & evidence

ORD record
ord-998194fb0d294d21bb06d69101fa0014
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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