Hydrochloric Acid → {8-Fluoro-2-[4-(3,4-difluorophenyl)-1-piperazinyl]-3-[2-methoxy-5-(trifluoromethyl)phenyl]-3,4-dihydro-4-quinazolinyl}acetic acid
Reaction equation
[ClH:45].[F:1][c:2]1[cH:3][cH:4][cH:5][c:6]2[c:11]1[N:10]=[C:9]([N:12]1[CH2:13][CH2:14][N:15]([c:18]3[cH:19][c:20]([F:25])[c:21]([F:24])[cH:22][cH:23]3)[CH2:16][CH2:17]1)[N:8]([c:26]1[c:27]([O:36][CH3:37])[cH:28][cH:29][c:30]([C:32]([F:33])([F:34])[F:35])[cH:31]1)[CH:7]2[CH2:38][C:39](=[O:40])[O:41][CH3:42].[Na+:44].[O:46]1[CH2:47][CH2:48][O:49][CH2:50][CH2:51]1.[OH-:43]>>[F:1][c:2]1[cH:3][cH:4][cH:5][c:6]2[c:11]1[N:10]=[C:9]([N:12]1[CH2:13][CH2:14][N:15]([c:18]3[cH:19][c:20]([F:25])[c:21]([F:24])[cH:22][cH:23]3)[CH2:16][CH2:17]1)[N:8]([c:26]1[c:27]([O:36][CH3:37])[cH:28][cH:29][c:30]([C:32]([F:33])([F:34])[F:35])[cH:31]1)[CH:7]2[CH2:38][C:39](=[O:40])[OH:41]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-cf5fd9e1194b4937898ba76f7cb36dd2
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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