Propylamine → 1,1,1-Trifluoro-3-[(1-phenyl-1H-indazol-4-yl)amino]-2-[(propylamino)methyl]-2-propanol

HRID 2138927Notes

Reaction equation

HRID 2138927 reaction equation
[CH2:1]([CH3:2])[NH:3][CH2:4][C:5]([C:6]([F:7])([F:8])[F:9])([OH:10])[CH2:11][NH:12][c:13]1[c:14]2[cH:15][n:16][n:17](-[c:22]3[cH:23][cH:24][cH:25][cH:26][cH:27]3)[c:18]2[cH:19][cH:20][cH:21]1.[CH2:28]([NH2:29])[CH2:30][CH3:31].[c:32]1(-[n:33]2[c:34]3[cH:35][cH:36][cH:37][c:38]([NH:39][CH2:40][C:41]4([C:42]([F:43])([F:44])[F:45])[CH2:46][O:47]4)[c:48]3[cH:49][n:50]2)[cH:51][cH:52][cH:53][cH:54][cH:55]1>>[CH2:1]([CH2:2][CH3:28])[NH:3][CH2:4][C:5]([C:6]([F:7])([F:8])[F:9])([OH:10])[CH2:11][NH:12][c:13]1[c:14]2[cH:15][n:16][n:17](-[c:22]3[cH:23][cH:24][cH:25][cH:26][cH:27]3)[c:18]2[cH:19][cH:20][cH:21]1

Participants

4

Reactant 3

HCID 7852PropylamineHCID 249380531-Phenyl-N-{[2-(trifluoromethyl)-2-oxiranyl]methyl}-1H-indazol-4-amineHCID 593241573-(Ethylamino)-1,1,1-trifluoro-2-{[(1-phenyl-1H-indazol-4-yl)amino]methyl}-2-propanol

Product 1

HCID 593241711,1,1-Trifluoro-3-[(1-phenyl-1H-indazol-4-yl)amino]-2-[(propylamino)methyl]-2-propanol

Sources & evidence

ORD record
ord-83f2fc4559654fcda94bd7321a51db6f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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