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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2139041Generated: October 28, 2026

Dichloromethane → 5-Chloro-1-(2,6-difluorophenyl)-7-(methylthio)-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1H)-one

https://huagongshe.com/reaction/2139041

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
ReactantBis-(1H-imidazol-2-YL)-methanoneHCID 5250894—
Reactant5-(Aminomethyl)-6-chloro-N-(2,6-difluorophenyl)-2-(methylthio)-4-pyrimidinamineHCID 57530543—
Product5-Chloro-1-(2,6-difluorophenyl)-7-(methylthio)-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1H)-oneHCID 57530500—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (4/10)
ORD IDord-ae1fc8ff8aca4743964864671a5611ec
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (4/10)