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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2139091Generated: October 28, 2026

Methanol → tert-butyl 5-[2-amino-3-(3,5-difluorophenyl)-1-hydroxypropyl]-2,2-diphenylmorpholine-4-carboxylate

https://huagongshe.com/reaction/2139091

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanolHCID 887—
ReactantSodium ionHCID 923—
ReactantWaterHCID 962—
ReactantNickel DichlorideHCID 24385—
ReactantBorohydrideHCID 28123—
ReactantHCID 178451573HCID 178451573—
Producttert-butyl 5-[2-amino-3-(3,5-difluorophenyl)-1-hydroxypropyl]-2,2-diphenylmorpholine-4-carboxylateHCID 178451574—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (4/10)
ORD IDord-2a1b8805f5f948debe131fb5c14a615a
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (4/10)