Dichloromethane → Ethyl 1-benzoyl-3-piperidinecarboxylate

HRID 2139466Notes

Reaction equation

HRID 2139466 reaction equation
[C:21]([c:22]1[cH:23][cH:24][cH:25][cH:26][cH:27]1)(=[O:28])[Cl:29].[CH:12]([N:13]([CH:14]([CH3:15])[CH3:16])[CH2:17][CH3:18])([CH3:19])[CH3:20].[Cl:30][CH2:31][Cl:32].[NH:1]1[CH2:2][CH:3]([C:4](=[O:5])[O:6][CH2:7][CH3:8])[CH2:9][CH2:10][CH2:11]1>>[N:1]1([C:21]([c:22]2[cH:23][cH:24][cH:25][cH:26][cH:27]2)=[O:28])[CH2:2][CH:3]([C:4](=[O:5])[O:6][CH2:7][CH3:8])[CH2:9][CH2:10][CH2:11]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 7412Benzoyl chlorideHCID 81531DiisopropylethylamineHCID 98969Ethyl nipecotate

Product 1

HCID 3784394Ethyl 1-benzoyl-3-piperidinecarboxylate

Sources & evidence

ORD record
ord-4d5cc7db906748d5adcb0976b480554c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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