Diisopropylethylamine → 3-Amino-6-methoxy-N-(3,3,3-trifluoro-2-(4-methoxybenzylamino)-2-methylpropyl)-5-(trifluoromethyl)picolinamide

HRID 2139575Notes

Reaction equation

HRID 2139575 reaction equation
[CH:35]([N:36]([CH2:37][CH3:38])[CH:39]([CH3:40])[CH3:41])([CH3:42])[CH3:43].[F:17][C:18]([C:19]([CH2:20][NH2:21])([NH:22][CH2:23][c:24]1[cH:25][cH:26][c:27]([O:30][CH3:31])[cH:28][cH:29]1)[CH3:32])([F:33])[F:34].[NH2:1][c:2]1[c:3]([C:14](=[O:15])[OH:16])[n:4][c:5]([O:12][CH3:13])[c:6]([C:8]([F:9])([F:10])[F:11])[cH:7]1>>[NH2:1][c:2]1[c:3]([C:14](=[O:16])[NH:21][CH2:20][C:19]([C:18]([F:17])([F:33])[F:34])([NH:22][CH2:23][c:24]2[cH:25][cH:26][c:27]([O:30][CH3:31])[cH:28][cH:29]2)[CH3:32])[n:4][c:5]([O:12][CH3:13])[c:6]([C:8]([F:9])([F:10])[F:11])[cH:7]1

Participants

4

Reactant 3

HCID 81531DiisopropylethylamineHCID 584423203-Amino-6-methoxy-5-trifluoromethyl-pyridine-2-carboxylic acidHCID 584423453,3,3-trifluoro-N2-(4-methoxybenzyl)-2-methylpropane-1,2-diamine

Product 1

HCID 584423323-Amino-6-methoxy-N-(3,3,3-trifluoro-2-(4-methoxybenzylamino)-2-methylpropyl)-5-(trifluoromethyl)picolinamide

Sources & evidence

ORD record
ord-56d069a9f4c94a159f18b9fe7f736234
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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