Dichloromethane → 4-amino-6-bromo-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidine

HRID 2139634Notes

Reaction equation

HRID 2139634 reaction equation
[Br:24][N:25]1[C:26](=[O:27])[CH2:28][CH2:29][C:30]1=[O:31].[CH3:32][C:33]([N:34]([CH3:35])[CH3:36])=[O:37].[Cl:38][CH2:39][Cl:40].[NH2:1][c:2]1[c:3]2[c:4]([n:5][cH:6][n:7]1)[nH:8][cH:9][c:10]2-[c:11]1[cH:12][cH:13][c:14]([O:17][c:18]2[cH:19][cH:20][cH:21][cH:22][cH:23]2)[cH:15][cH:16]1>>[NH2:1][c:2]1[c:3]2[c:4]([n:5][cH:6][n:7]1)[nH:8][c:9]([Br:24])[c:10]2-[c:11]1[cH:12][cH:13][c:14]([O:17][c:18]2[cH:19][cH:20][cH:21][cH:22][cH:23]2)[cH:15][cH:16]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 31374DimethylacetamideHCID 67184N-bromobutanimideHCID 120422345-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine

Product 1

HCID 227362094-amino-6-bromo-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidine

Sources & evidence

ORD record
ord-baf62c3701094cc7b1faeee0ae830945
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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