Potassium Cation → 3-Oxo-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine-6-carbaldehyde

HRID 2139749Notes

Reaction equation

HRID 2139749 reaction equation
[Br:20][c:21]1[cH:22][cH:23][c:24]2[c:30]([n:31]1)[NH:29][C:27](=[O:28])[CH2:26][O:25]2.[CH2:49]1[O:50][CH2:51][CH2:52][O:53][CH2:54]1.[CH3:56][CH2:57][O:58][C:59]([CH3:60])=[O:61].[CH:1](=[CH:2][c:3]1[cH:4][cH:5][cH:6][cH:7][cH:8]1)[c:9]1[cH:10][cH:11][c:12]2[c:17]([n:18]1)[NH:16][C:15](=[O:19])[CH2:14][O:13]2.[K+:43].[K+:44].[O-:45][C:46]([O-:47])=[O:48].[OH2:55].[c:32]1([CH:33]=[CH:34][B:35]([OH:36])[OH:37])[cH:38][cH:39][cH:40][cH:41][cH:42]1.[cH:62]1[cH:63][cH:64][c:65]([P:66]([Pd:67]([P:68]([c:69]2[cH:70][cH:71][cH:72][cH:73][cH:74]2)([c:75]2[cH:76][cH:77][cH:78][cH:79][cH:80]2)[c:81]2[cH:82][cH:83][cH:84][cH:85][cH:86]2)([P:87]([c:88]2[cH:89][cH:90][cH:91][cH:92][cH:93]2)([c:94]2[cH:95][cH:96][cH:97][cH:98][cH:99]2)[c:100]2[cH:101][cH:102][cH:103][cH:104][cH:105]2)[P:106]([c:107]2[cH:108][cH:109][cH:110][cH:111][cH:112]2)([c:113]2[cH:114][cH:115][cH:116][cH:117][cH:118]2)[c:119]2[cH:120][cH:121][cH:122][cH:123][cH:124]2)([c:125]2[cH:126][cH:127][cH:128][cH:129][cH:130]2)[c:131]2[cH:132][cH:133][cH:134][cH:135][cH:136]2)[cH:137][cH:138]1>>[CH:1]([c:9]1[cH:10][cH:11][c:12]2[c:17]([n:18]1)[NH:16][C:15](=[O:19])[CH2:14][O:13]2)=[O:25]

Participants

10

Reactant 9

HCID 813Potassium Cation2×HCID 962WaterHCID 8857Ethyl AcetateHCID 19660Carbonate IonHCID 312751,4-DioxaneHCID 27343812-Phenylvinylboronic acidHCID 218737726-Bromo-2H-pyrido[3,2-B][1,4]oxazin-3(4H)-oneHCID 684438466-Styryl-4H-pyrido[3,2-b][1,4]oxazin-3-oneHCID 178420554HCID 178420554, compound

Product 1

HCID 218737373-Oxo-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine-6-carbaldehyde

Sources & evidence

ORD record
ord-c6f394d6d03746cfacc2ab9c000cb8c0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

Loading…