Dichloromethane → methyl 6-[[3-cyclohexyl-2-[3-(2,6-difluorophenoxy)-5-oxo-2H-pyrrol-1-yl]propanoyl]amino]pyridine-3-carboxylate
Reaction equation
[Br:44][P+:45]([N:46]1[CH2:47][CH2:48][CH2:49][CH2:50]1)([N:51]1[CH2:52][CH2:53][CH2:54][CH2:55]1)[N:56]1[CH2:57][CH2:58][CH2:59][CH2:60]1.[CH3:70][O:71][C:72]([c:73]1[cH:74][n:75][c:76]([NH2:79])[cH:77][cH:78]1)=[O:80].[CH:1]1([CH2:7][CH:8]([C:9](=[O:10])[NH:11][c:12]2[cH:13][cH:14][n:15]([CH2:16][C:17]([OH:18])([CH3:19])[CH3:20])[n:21]2)[N:22]2[C:23](=[O:36])[CH:24]=[C:25]([O:27][c:28]3[c:29]([F:35])[cH:30][cH:31][cH:32][c:33]3[F:34])[CH2:26]2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1.[CH:61]([N:62]([CH2:63][CH3:64])[CH:65]([CH3:66])[CH3:67])([CH3:68])[CH3:69].[Cl:81][CH2:82][Cl:83].[P-:37]([F:38])([F:39])([F:40])([F:41])([F:42])[F:43]>>[CH:1]1([CH2:7][CH:8]([C:9](=[O:10])[NH:11][c:76]2[n:75][cH:74][c:73]([C:72]([O:71][CH3:70])=[O:80])[cH:78][cH:77]2)[N:22]2[C:23](=[O:36])[CH:24]=[C:25]([O:27][c:28]3[c:29]([F:35])[cH:30][cH:31][cH:32][c:33]3[F:34])[CH2:26]2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-bf26701757ad49de88da673ec2b6adf4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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