Dichloromethane → Dimethyl 2-(3,4-difluorobenzyl)piperidine-1,4-dicarboxylate
Reaction equation
[C:29]([O:30][CH3:31])(=[O:32])[Cl:33].[CH:20]([N:21]([CH2:22][CH3:23])[CH:24]([CH3:25])[CH3:26])([CH3:27])[CH3:28].[Cl:34][CH2:35][Cl:36].[F:1][c:2]1[cH:3][c:4]([CH2:5][CH:6]2[NH:7][CH2:8][CH2:9][CH:10]([C:12](=[O:13])[O:14][CH3:15])[CH2:11]2)[cH:16][cH:17][c:18]1[F:19]>>[F:1][c:2]1[cH:3][c:4]([CH2:5][CH:6]2[N:7]([C:29]([O:30][CH3:31])=[O:32])[CH2:8][CH2:9][CH:10]([C:12](=[O:13])[O:14][CH3:15])[CH2:11]2)[cH:16][cH:17][c:18]1[F:19]Participants
5
Sources & evidence
- ORD record
- ord-9e83f3c4548c4b1786b62d6ecd8a5854
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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