Hydrochloric Acid → Methyl 5-[4-(difluoromethoxy)phenyl]nicotinate
Reaction equation
[C:27](=[O:28])([O-:29])[O-:30].[CH3:13][O:14][C:15](=[O:16])[c:17]1[cH:18][c:19]([B:23]([OH:24])[OH:25])[cH:20][n:21][cH:22]1.[ClH:12].[ClH:26].[F:1][CH:2]([O:3][c:4]1[cH:5][cH:6][c:7]([Br:10])[cH:8][cH:9]1)[F:11].[K+:31].[K+:32]>>[F:1][CH:2]([O:3][c:4]1[cH:5][cH:6][c:7](-[c:19]2[cH:18][c:17]([C:15]([O:14][CH3:13])=[O:16])[cH:22][n:21][cH:20]2)[cH:8][cH:9]1)[F:11]Participants
6
Sources & evidence
- ORD record
- ord-dafe248227f64c55a35f2ec581734514
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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