Lithium ion → 4-Bromo-2,6-difluorobenzyl alcohol

HRID 2140368Notes

Reaction equation

HRID 2140368 reaction equation
[Br:1][c:2]1[cH:3][c:4]([F:9])[cH:5][c:6]([F:8])[cH:7]1.[CH:21]([N-:22][CH:23]([CH3:24])[CH3:25])([CH3:26])[CH3:27].[F:10][c:11]1[cH:12][c:13]([CH3:14])[cH:15][c:16]([F:17])[c:18]1[CH2:19][OH:20].[Li+:28]>>[Br:1][c:2]1[cH:3][c:4]([F:9])[c:5]([CH2:19][OH:20])[c:6]([F:8])[cH:7]1

Participants

5

Reactant 4

HCID 28486Lithium ionHCID 1363131-Bromo-3,5-difluorobenzeneHCID 5062348DiisopropylamideHCID 18550098(2,6-Difluoro-4-methylphenyl)methanol

Product 1

HCID 27733034-Bromo-2,6-difluorobenzyl alcohol

Sources & evidence

ORD record
ord-3c2a174965e0403faa3d2b32dabdd8c3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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