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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2140477Generated: October 27, 2026

3-Bromo-2-fluoro-5-methylpyridine → 8-(2-Fluoro-5-methylpyridin-3-yl)-2-(4-(trifluoromethoxy)phenyl)-2,8-diazaspiro[4.5]decan-1-one

https://huagongshe.com/reaction/2140477

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Bromo-2-fluoro-5-methylpyridineHCID 21816563—
Reactant2-(4-(Trifluoromethoxy)phenyl)-2,8-diazaspiro[4.5]decan-1-oneHCID 66742759—
Product8-(2-Fluoro-5-methylpyridin-3-yl)-2-(4-(trifluoromethoxy)phenyl)-2,8-diazaspiro[4.5]decan-1-oneHCID 56655688—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (4/10)
ORD IDord-ef40eeecc4f148cc90aa7f1b78a26276
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (4/10)