1,8-Diazabicyclo(5.4.0)undec-7-ene → Methyl 3-cyclopentyl-3-[4-(7-[2-(trimethylsilyl)ethoxy]methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]propanoate

HRID 2140484Notes

Reaction equation

HRID 2140484 reaction equation
[CH2:34]1[CH2:35][CH2:36][C:37]2=[N:42][CH2:41][CH2:40][CH2:39][N:38]2[CH2:43][CH2:44]1.[CH:23]1([CH:28]=[CH:29][C:30](=[O:31])[O:32][CH3:33])[CH2:24][CH2:25][CH2:26][CH2:27]1.[nH:1]1[n:2][cH:3][c:4](-[c:6]2[c:7]3[c:8]([n:9][cH:10][n:11]2)[n:12]([CH2:15][O:16][CH2:17][CH2:18][Si:19]([CH3:20])([CH3:21])[CH3:22])[cH:13][cH:14]3)[cH:5]1>>[n:1]1([CH:28]([CH:23]2[CH2:24][CH2:25][CH2:26][CH2:27]2)[CH2:29][C:30](=[O:31])[O:32][CH3:33])[n:2][cH:3][c:4](-[c:6]2[c:7]3[c:8]([n:9][cH:10][n:11]2)[n:12]([CH2:15][O:16][CH2:17][CH2:18][Si:19]([CH3:20])([CH3:21])[CH3:22])[cH:13][cH:14]3)[cH:5]1

Participants

4

Reactant 3

HCID 811841,8-Diazabicyclo(5.4.0)undec-7-eneHCID 426313464-(1H-Pyrazol-4-yl)-7-(2-(trimethylsilyl)ethoxy)methyl-7 H-pyrrolo(2,3-d)-pyrimidineHCID 66586510Methyl 3-cyclopentylprop-2-enoate

Product 1

HCID 57478032Methyl 3-cyclopentyl-3-[4-(7-[2-(trimethylsilyl)ethoxy]methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]propanoate

Sources & evidence

ORD record
ord-b423548ffb604f43bf12d27cf8aafc97
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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