Dichloromethane → tert-butyl N-[1-(2-chloro-7-methylquinazolin-4-yl)pyrrolidin-3-yl]carbamate
Reaction equation
[CH3:27][CH2:28][N:29]([CH2:30][CH3:31])[CH2:32][CH3:33].[Cl:1][c:2]1[n:3][c:4]2[cH:5][c:6]([CH3:13])[cH:7][cH:8][c:9]2[c:10]([Cl:12])[n:11]1.[Cl:34][CH2:35][Cl:36].[NH:14]1[CH2:15][CH:16]([NH:19][C:20]([O:21][C:22]([CH3:23])([CH3:24])[CH3:25])=[O:26])[CH2:17][CH2:18]1>>[Cl:1][c:2]1[n:3][c:4]2[cH:5][c:6]([CH3:13])[cH:7][cH:8][c:9]2[c:10]([N:14]2[CH2:15][CH:16]([NH:19][C:20]([O:21][C:22]([CH3:23])([CH3:24])[CH3:25])=[O:26])[CH2:17][CH2:18]2)[n:11]1Participants
5
Sources & evidence
- ORD record
- ord-8933b04294d544669350f16836fe19d8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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