Hydroxide → 3-[(2,6-Dichloro-4-hydroxyphenyl)methyl]-1-[4-tri(propan-2-yl)silyloxycyclohexyl]pyrrolidin-2-one

HRID 2141003Notes

Reaction equation

HRID 2141003 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][c:11]([Cl:40])[c:12]([CH2:13][CH:14]2[C:15](=[O:36])[N:16]([CH:19]3[CH2:20][CH2:21][CH:22]([O:25][Si:26]([CH:27]([CH3:28])[CH3:29])([CH:30]([CH3:31])[CH3:32])[CH:33]([CH3:34])[CH3:35])[CH2:23][CH2:24]3)[CH2:17][CH2:18]2)[c:37]([Cl:39])[cH:38]1.[CH3:43][CH2:44][O:45][C:46](=[O:47])[CH3:48].[H:41][H:42].[OH-:49].[OH-:51].[Pd+2:50]>>[OH:8][c:9]1[cH:10][c:11]([Cl:40])[c:12]([CH2:13][CH:14]2[C:15](=[O:36])[N:16]([CH:19]3[CH2:20][CH2:21][CH:22]([O:25][Si:26]([CH:27]([CH3:28])[CH3:29])([CH:30]([CH3:31])[CH3:32])[CH:33]([CH3:34])[CH3:35])[CH2:23][CH2:24]3)[CH2:17][CH2:18]2)[c:37]([Cl:39])[cH:38]1

Participants

6

Reactant 5

HCID 961Hydroxide2×HCID 8857Ethyl AcetateHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 666222243-[(2,6-Dichloro-4-phenylmethoxyphenyl)methyl]-1-[4-tri(propan-2-yl)silyloxycyclohexyl]pyrrolidin-2-oneHCID 178418361HCID 178418361, compound

Product 1

HCID 666217573-[(2,6-Dichloro-4-hydroxyphenyl)methyl]-1-[4-tri(propan-2-yl)silyloxycyclohexyl]pyrrolidin-2-one

Sources & evidence

ORD record
ord-fc75777f9a3641f69da4f07b0ffee80a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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