Dichloromethane → Ethyl 2-(1H-indol-2-yl)-2-methylpropanoate

HRID 2141056Notes

Reaction equation

HRID 2141056 reaction equation
[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[C:6]([CH3:7])([CH3:8])[c:9]1[n:10]([C:18]([O:19][C:20]([CH3:21])([CH3:22])[CH3:23])=[O:24])[c:11]2[cH:12][cH:13][cH:14][cH:15][c:16]2[cH:17]1.[Cl:25][CH2:26][Cl:27].[F:28][C:29]([F:30])([F:31])[C:32]([OH:33])=[O:34]>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[C:6]([CH3:7])([CH3:8])[c:9]1[nH:10][c:11]2[cH:12][cH:13][cH:14][cH:15][c:16]2[cH:17]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 53439126tert-Butyl 2-(1-ethoxy-2-methyl-1-oxopropan-2-yl)-1H-indole-1-carboxylate

Product 1

HCID 53438556Ethyl 2-(1H-indol-2-yl)-2-methylpropanoate

Sources & evidence

ORD record
ord-523b4c59362d40619b772494430c6f76
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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