Tetrahydrofuran → 4-((4-Bromothiazol-2-yl)(5-ethoxy-2-fluoro-3-isopropoxyphenyl)methylamino)benzonitrile
Reaction equation
[Br:1][c:2]1[s:3][cH:4][c:5]([Br:7])[n:6]1.[CH2:13]([CH3:14])[O:15][c:16]1[cH:17][c:18]([O:33][CH:34]([CH3:35])[CH3:36])[c:19]([F:32])[c:20]([CH:21]=[N:22][c:23]2[cH:24][cH:25][c:26]([C:27]#[N:28])[cH:29][cH:30]2)[cH:31]1.[CH2:37]1[O:38][CH2:39][CH2:40][CH2:41]1.[CH3:8][CH2:9][CH2:10][CH2:11][Li:12]>>[c:2]1([N:22]([CH2:21][c:20]2[c:19]([F:32])[c:18]([O:33][CH:34]([CH3:35])[CH3:36])[cH:17][c:16]([O:15][CH2:13][CH3:14])[cH:31]2)[c:23]2[cH:24][cH:25][c:26]([C:27]#[N:28])[cH:29][cH:30]2)[s:3][cH:4][c:5]([Br:7])[n:6]1Participants
5
Sources & evidence
- ORD record
- ord-763030a93d2141cf9d7b7092473c726c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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