Acetate → 2-(2-Fluorophenyl)-5-nitropyridine

HRID 2141259Notes

Reaction equation

HRID 2141259 reaction equation
[Br:1][c:2]1[n:3][cH:4][c:5]([N+:8](=[O:9])[O-:10])[cH:6][cH:7]1.[C:56]([O-:57])(=[O:58])[CH3:59].[C:61]([O-:62])(=[O:63])[CH3:64].[CH3:46][c:47]1[cH:48][cH:49][cH:50][cH:51][cH:52]1.[CH3:53][CH2:54][OH:55].[F:11][c:12]1[c:13]([B:18]([OH:19])[OH:20])[cH:14][cH:15][cH:16][cH:17]1.[Na+:40].[Na+:41].[O-:42][C:43](=[O:44])[O-:45].[Pd+2:60].[c:21]1([P:22]([c:23]2[cH:24][cH:25][cH:26][cH:27][cH:28]2)[c:29]2[cH:30][cH:31][cH:32][cH:33][cH:34]2)[cH:35][cH:36][cH:37][cH:38][cH:39]1>>[c:2]1(-[c:13]2[c:12]([F:11])[cH:17][cH:16][cH:15][cH:14]2)[n:3][cH:4][c:5]([N+:8](=[O:9])[O-:10])[cH:6][cH:7]1

Participants

10

Reactant 9

HCID 175Acetate2×HCID 702EthanolHCID 923Sodium ion2×HCID 1140TolueneHCID 11776TriphenylphosphineHCID 19660Carbonate IonHCID 782402-Bromo-5-nitropyridineHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 27343542-Fluorophenylboronic acid

Product 1

HCID 685377752-(2-Fluorophenyl)-5-nitropyridine

Sources & evidence

ORD record
ord-b102144166384d1c90d52dd4c4237c29
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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