Dichloromethane → HCID 57955166, compound

HRID 2141314Notes

Reaction equation

[CH2:56]([Cl:57])[Cl:58].[NH2:1][c:2]1[n:3][cH:4][n:5][n:6]2[c:7]1[c:8](-[c:27]1[cH:28][c:29]([F:48])[c:30]([NH:33][C:34]([NH:35][c:36]3[c:37]([F:46])[cH:38][cH:39][c:40]([C:42]([F:43])([F:44])[F:45])[cH:41]3)=[O:47])[cH:31][cH:32]1)[c:9]([CH2:24][O:25][CH3:26])[c:10]2[CH:11]1[CH2:12][CH2:13][N:14]([C:17]([O:18][C:19]([CH3:20])([CH3:21])[CH3:22])=[O:23])[CH2:15][CH2:16]1.[OH:49][C:50]([C:51]([F:52])([F:53])[F:54])=[O:55]>>[NH2:1][c:2]1[n:3][cH:4][n:5][n:6]2[c:7]1[c:8](-[c:27]1[cH:28][c:29]([F:48])[c:30]([NH:33][C:34]([NH:35][c:36]3[c:37]([F:46])[cH:38][cH:39][c:40]([C:42]([F:43])([F:44])[F:45])[cH:41]3)=[O:47])[cH:31][cH:32]1)[c:9]([CH2:24][O:25][CH3:26])[c:10]2[CH:11]1[CH2:12][CH2:13][NH:14][CH2:15][CH2:16]1

Participants

Reactant 3

HCID 6344Dichloromethane

HCID 6422Trifluoroacetic acid

HCID 66641290Tert-butyl 4-{4-amino-5-[3-fluoro-4-({[2-fluoro-5-(trifluoromethyl)phenyl]carbamoyl}amino)phenyl]-6-(methoxymethyl)pyrrolo[2,1-f][1,2,4]triazin-7-yl}piperidine-1-carboxylate

Product 1

HCID 57955166HCID 57955166, compound

Sources & evidence

ORD record: ord-977477df3d19405f8a4e494befaa1652
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (4/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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