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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2141514Generated: November 4, 2026

1,2-Dimethoxyethane → 6-[2-(4-Cyano-phenyl)-2H-pyrazol-3-yl]-5-methyl-3-oxo-4-(3-trifluoromethyl-phenyl)-3,4-dihydro-pyrazine-2-carboxylic acid methylamide

https://huagongshe.com/reaction/2141514

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-DimethoxyethaneHCID 8071—
ReactantCarbonate IonHCID 19660—
ReactantCesium cationHCID 104967—
Reactant6-Bromo-N,5-dimethyl-3-oxo-4-[3-(trifluoromethyl)phenyl]-3,4-dihydropyrazine-2-carboxamideHCID 66738659—
Reactant[1-(4-cyanophenyl)-1H-pyrazol-5-yl]boronic acidHCID 66738661—
Product6-[2-(4-Cyano-phenyl)-2H-pyrazol-3-yl]-5-methyl-3-oxo-4-(3-trifluoromethyl-phenyl)-3,4-dihydro-pyrazine-2-carboxylic acid methylamideHCID 24890140—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (4/10)
ORD IDord-1b7269da41064175bd2889e552b70382
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (4/10)