Dichloromethane → 5-Bromo-3-(5-(2,3-dichlorophenyl)thiazol-4-yl)pyridin-2-amine
Reaction equation
[CH2:38]([Cl:39])[Cl:40].[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([CH2:7][NH:8][c:9]2[n:10][cH:11][c:12]([Br:28])[cH:13][c:14]2-[c:15]2[n:16][cH:17][s:18][c:19]2-[c:20]2[c:21]([Cl:27])[c:22]([Cl:26])[cH:23][cH:24][cH:25]2)[cH:29][cH:30]1.[F:31][C:32]([F:33])([F:34])[C:35]([OH:36])=[O:37]>>[NH2:8][c:9]1[n:10][cH:11][c:12]([Br:28])[cH:13][c:14]1-[c:15]1[n:16][cH:17][s:18][c:19]1-[c:20]1[c:21]([Cl:27])[c:22]([Cl:26])[cH:23][cH:24][cH:25]1Participants
4
Sources & evidence
- ORD record
- ord-a6bccdb67ad7444dae34e06832ae58ea
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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