N-methyl-2-pyrrolidone → N-(4-cyano-2-methyl-3-(trifluoromethyl)phenyl)pivalamide

HRID 2141653Notes

Reaction equation

HRID 2141653 reaction equation
[CH3:23][N:24]1[CH2:25][CH2:26][CH2:27][C:28]1=[O:29].[Cl:1][c:2]1[c:3]([C:16]([F:17])([F:18])[F:19])[c:4]([CH3:15])[c:5]([NH:8][C:9]([C:10]([CH3:11])([CH3:12])[CH3:13])=[O:14])[cH:6][cH:7]1.[Cu:20][C:21]#[N:22]>>[c:2]1([C:21]#[N:22])[c:3]([C:16]([F:17])([F:18])[F:19])[c:4]([CH3:15])[c:5]([NH:8][C:9]([C:10]([CH3:11])([CH3:12])[CH3:13])=[O:14])[cH:6][cH:7]1

Participants

4

Reactant 3

HCID 13387N-methyl-2-pyrrolidoneHCID 21874848N-[4-chloro-2-methyl-3-(trifluoromethyl)phenyl]-2,2-dimethylpropanamideHCID 178418546HCID 178418546, compound

Product 1

HCID 21875020N-(4-cyano-2-methyl-3-(trifluoromethyl)phenyl)pivalamide

Sources & evidence

ORD record
ord-a5409cf680fc475085020c316d40317e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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