Methanol → [3-(4-Acetylbenzyl)-4-difluoromethoxy-2-ethyl-8-fluoroquinolin-5-yloxy]acetic acid
Reaction equation
[CH3:1][O:2][C:3]([CH2:4][O:5][c:6]1[c:7]2[c:8]([O:29][CH:30]([F:31])[F:32])[c:9]([CH2:19][c:20]3[cH:21][cH:22][c:23]([C:26]([CH3:27])=[O:28])[cH:24][cH:25]3)[c:10]([CH2:17][CH3:18])[n:11][c:12]2[c:13]([F:16])[cH:14][cH:15]1)=[O:33].[CH3:36][OH:37].[Li+:34].[OH-:35]>>[O:2]=[C:3]([CH2:4][O:5][c:6]1[c:7]2[c:8]([O:29][CH:30]([F:31])[F:32])[c:9]([CH2:19][c:20]3[cH:21][cH:22][c:23]([C:26]([CH3:27])=[O:28])[cH:24][cH:25]3)[c:10]([CH2:17][CH3:18])[n:11][c:12]2[c:13]([F:16])[cH:14][cH:15]1)[OH:33]Participants
5
Sources & evidence
- ORD record
- ord-10a1f7f318f34c70a5f57638868f8d3e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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