Dimethyl Sulfoxide → 5-chloro-N-(2,4-dimethoxybenzyl)-2-fluoro-4-{2-[3-nitro-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazol-4-yl]-4-(trifluoromethyl)phenoxy}-N-1,3,4-thiadiazol-2-ylbenzenesulfonamide
Reaction equation
[C:26](=[O:27])([O-:28])[O-:29].[CH3:61][S:62](=[O:63])[CH3:64].[CH3:65][CH2:66][O:67][C:68](=[O:69])[CH3:70].[Cl:32][c:33]1[c:34]([F:60])[cH:35][c:36]([F:59])[c:37]([S:39](=[O:40])(=[O:41])[N:42]([c:43]2[s:44][cH:45][n:46][n:47]2)[CH2:48][c:49]2[c:50]([O:57][CH3:58])[cH:51][c:52]([O:55][CH3:56])[cH:53][cH:54]2)[cH:38]1.[K+:30].[K+:31].[N+:1](=[O:2])([O-:3])[c:4]1[n:5][n:6]([CH:20]2[O:21][CH2:22][CH2:23][CH2:24][CH2:25]2)[cH:7][c:8]1-[c:9]1[c:10]([OH:19])[cH:11][cH:12][c:13]([C:15]([F:16])([F:17])[F:18])[cH:14]1>>[N+:1](=[O:2])([O-:3])[c:4]1[n:5][n:6]([CH:20]2[O:21][CH2:22][CH2:23][CH2:24][CH2:25]2)[cH:7][c:8]1-[c:9]1[c:10]([O:19][c:34]2[c:33]([Cl:32])[cH:38][c:37]([S:39](=[O:40])(=[O:41])[N:42]([c:43]3[s:44][cH:45][n:46][n:47]3)[CH2:48][c:49]3[c:50]([O:57][CH3:58])[cH:51][c:52]([O:55][CH3:56])[cH:53][cH:54]3)[c:36]([F:59])[cH:35]2)[cH:11][cH:12][c:13]([C:15]([F:16])([F:17])[F:18])[cH:14]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-b515674f058c4cbe8da98aa3cda5605c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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