Sodium ion → Tert-butyl 4-cyano-4-(2-hydroxyethyl)piperidine-1-carboxylate

HRID 214203Notes

Reaction equation

HRID 214203 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11]([CH2:14][CH:15]([CH2:16][OH:17])[OH:18])([C:19]#[N:20])[CH2:12][CH2:13]1.[I+3:21]([O-:22])([O-:23])([O-:24])[O-:25].[Na+:26].[O:28]1[CH2:29][CH2:30][CH2:31][CH2:32]1.[OH2:27]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11]([CH2:14][CH2:15][OH:18])([C:19]#[N:20])[CH2:12][CH2:13]1

Participants

6

Reactant 5

HCID 923Sodium ionHCID 962WaterHCID 8028TetrahydrofuranHCID 167232PeriodateHCID 600641754-Cyano-4-(2,3-dihydroxypropyl)piperidine-1-carboxylic acid tert-butyl ester

Product 1

HCID 60064207Tert-butyl 4-cyano-4-(2-hydroxyethyl)piperidine-1-carboxylate

Sources & evidence

ORD record
ord-60b9e87940744c33a6425668171aaddb
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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