Ammonium → tert-Butyl (2-(7-(4-amino-2-fluorophenoxy)thieno[3,2-b]pyridin-2-yl)-1-methyl-1H-imidazol-5-yl)methyl(2-methoxyethyl)carbamate
Reaction equation
[CH3:42][OH:43].[Cl-:40].[F:1][c:2]1[c:3]([O:4][c:5]2[c:6]3[c:7]([n:8][cH:9][cH:10]2)[cH:11][c:12](-[c:14]2[n:15]([CH3:32])[c:16]([CH2:19][N:20]([C:21]([O:22][C:23]([CH3:24])([CH3:25])[CH3:26])=[O:27])[CH2:28][CH2:29][O:30][CH3:31])[cH:17][n:18]2)[s:13]3)[cH:33][cH:34][c:35]([N+:37]([O-:38])=[O:39])[cH:36]1.[NH4+:41].[OH2:44].[Zn:45]>>[F:1][c:2]1[c:3]([O:4][c:5]2[c:6]3[c:7]([n:8][cH:9][cH:10]2)[cH:11][c:12](-[c:14]2[n:15]([CH3:32])[c:16]([CH2:19][N:20]([C:21]([O:22][C:23]([CH3:24])([CH3:25])[CH3:26])=[O:27])[CH2:28][CH2:29][O:30][CH3:31])[cH:17][n:18]2)[s:13]3)[cH:33][cH:34][c:35]([NH2:37])[cH:36]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-ad2cb87989664cad958170e669021f48
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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