2-Bromoethanol → 5-(4-Bromo-2-fluorophenylamino)-3-(2-hydroxyethyl)-6,8-dimethylpyrido[2,3-d]pyrimidine-4,7(3H,8H)-dione
Reaction equation
[Br:1][CH2:2][CH2:3][OH:4].[Br:5][c:6]1[cH:7][c:8]([F:27])[c:9]([NH:12][c:13]2[c:14]([CH3:26])[c:15](=[O:25])[n:16]([CH3:24])[c:17]3[n:18][cH:19][nH:20][c:21](=[O:23])[c:22]23)[cH:10][cH:11]1>>[CH2:2]([CH2:3][OH:4])[n:20]1[cH:19][n:18][c:17]2[n:16]([CH3:24])[c:15](=[O:25])[c:14]([CH3:26])[c:13]([NH:12][c:9]3[c:8]([F:27])[cH:7][c:6]([Br:5])[cH:11][cH:10]3)[c:22]2[c:21]1=[O:23]Participants
3
Sources & evidence
- ORD record
- ord-d24837b576ec47c7b6b1b470c3335a93
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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