Bromide ion → 2-(8-Benzyloxy-5-chloro-quinolin-7-yl)-1-(3-pyrrolidin-1-ylmethyl-phenyl)-ethanol

HRID 2142704Notes

Reaction equation

HRID 2142704 reaction equation
[Br-:23].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[c:10]([CH2:20][CH:21]=[O:22])[cH:11][c:12]([Cl:19])[c:13]2[cH:14][cH:15][cH:16][n:17][c:18]12.[N:24]1([CH2:29][c:30]2[cH:31][c:32]([Mg+:36])[cH:33][cH:34][cH:35]2)[CH2:25][CH2:26][CH2:27][CH2:28]1.[O:37]1[CH2:38][CH2:39][CH2:40][CH2:41]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[c:10]([CH2:20][CH:21]([OH:22])[c:32]2[cH:31][c:30]([CH2:29][N:24]3[CH2:25][CH2:26][CH2:27][CH2:28]3)[cH:35][cH:34][cH:33]2)[cH:11][c:12]([Cl:19])[c:13]2[cH:14][cH:15][cH:16][n:17][c:18]12

Participants

5

Reactant 4

HCID 259Bromide ionHCID 8028TetrahydrofuranHCID 59829696[8-(Benzyloxy)-5-chloroquinolin-7-yl]acetaldehydeHCID 178507010HCID 178507010, compound

Product 1

HCID 671720482-(8-Benzyloxy-5-chloro-quinolin-7-yl)-1-(3-pyrrolidin-1-ylmethyl-phenyl)-ethanol

Sources & evidence

ORD record
ord-9efdd182096f4fab8bf154136c5ec77c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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