Hydrochloric Acid → 5,6-dichloro-1-{3-[4-(4-fluorobenzoyl)-1-piperidinyl]propyl}-1,3-dihydro-2H-benzimidazol-2-one
Reaction equation
[CH3:23][CH:24]([CH3:25])[CH2:26][C:27](=[O:28])[CH3:29].[CH3:30][S:31]([O:32][CH2:35][CH2:36][CH2:37][n:38]1[c:39](=[O:49])[nH:40][c:41]2[c:42]1[cH:43][c:44]([Cl:48])[c:45]([Cl:47])[cH:46]2)(=[O:33])=[O:34].[ClH:1].[F:2][c:3]1[cH:4][cH:5][c:6]([C:9](=[O:10])[CH:11]2[CH2:12][CH2:13][NH:14][CH2:15][CH2:16]2)[cH:7][cH:8]1.[Na+:17].[Na+:18].[O-:19][C:20](=[O:21])[O-:22].[OH2:50]>>[F:2][c:3]1[cH:4][cH:5][c:6]([C:9](=[O:10])[CH:11]2[CH2:12][CH2:13][N:14]([CH2:35][CH2:36][CH2:37][n:38]3[c:39](=[O:49])[nH:40][c:41]4[c:42]3[cH:43][c:44]([Cl:48])[c:45]([Cl:47])[cH:46]4)[CH2:15][CH2:16]2)[cH:7][cH:8]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-8995002c659f4588a6150080965e0977
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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