Tetrahydrofuran → 3-(4-Benzyloxy-2,6-dichloro-benzyl)-1-(cis-4-hydroxy-cyclohexyl)-pyrrolidin-2-one
Reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][c:11]([Cl:37])[c:12]([CH2:13][CH:14]2[C:15](=[O:33])[N:16]([CH:19]3[CH2:20][CH2:21][CH:22]([O:25][Si:26]([C:27]([CH3:28])([CH3:29])[CH3:30])([CH3:31])[CH3:32])[CH2:23][CH2:24]3)[CH2:17][CH2:18]2)[c:34]([Cl:36])[cH:35]1.[CH2:39]([N+:40]([CH2:41][CH2:42][CH2:43][CH3:44])([CH2:45][CH2:46][CH2:47][CH3:48])[CH2:49][CH2:50][CH2:51][CH3:52])[CH2:53][CH2:54][CH3:55].[CH2:56]1[O:57][CH2:58][CH2:59][CH2:60]1.[F-:38]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][c:11]([Cl:37])[c:12]([CH2:13][CH:14]2[C:15](=[O:33])[N:16]([CH:19]3[CH2:20][CH2:21][CH:22]([OH:25])[CH2:23][CH2:24]3)[CH2:17][CH2:18]2)[c:34]([Cl:36])[cH:35]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-29b055c5af914dcd85e6c714d9ee2625
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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