Water → Racemic 4'-fluoro-2'-(2-fluoro-2-methylpropoxy)-7'-(2-fluoropyridin-3-yl)-2,6-dihydrospiro[[1,4]oxazine-3,9'-xanthen]-5-amine
Reaction equation
[F:35][C:36]([F:37])([F:38])[S:39]([O:40][CH2:41][C:42]([CH3:43])([CH3:44])[F:45])(=[O:46])=[O:47].[NH2:1][C:2]1=[N:3][C:4]2([CH2:5][O:6][CH2:7]1)[c:8]1[cH:9][c:10](-[c:23]3[c:24]([F:29])[n:25][cH:26][cH:27][cH:28]3)[cH:11][cH:12][c:13]1[O:14][c:15]1[c:16]([F:22])[cH:17][c:18]([OH:21])[cH:19][c:20]12.[O:30]=[CH:31][N:32]([CH3:33])[CH3:34].[OH2:48]>>[NH2:1][C:2]1=[N:3][C:4]2([CH2:5][O:6][CH2:7]1)[c:8]1[cH:9][c:10](-[c:23]3[c:24]([F:29])[n:25][cH:26][cH:27][cH:28]3)[cH:11][cH:12][c:13]1[O:14][c:15]1[c:16]([F:22])[cH:17][c:18]([O:21][CH2:41][C:42]([CH3:43])([CH3:44])[F:45])[cH:19][c:20]12Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-28e6bdf675a74cc6880f08429f3dc5ce
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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