Dichloromethane → Ethyl 4-(2-pyrrolidin-2-ylethenyl)benzoate

HRID 2142996Notes

Reaction equation

HRID 2142996 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH:9]([CH:13]=[CH:14][c:15]2[cH:16][cH:17][c:18]([C:19](=[O:20])[O:21][CH2:22][CH3:23])[cH:24][cH:25]2)[CH2:10][CH2:11][CH2:12]1)([CH3:5])([CH3:6])[CH3:7].[Cl:33][CH2:34][Cl:35].[F:26][C:27]([F:28])([F:29])[C:30]([OH:31])=[O:32]>>[NH:8]1[CH:9]([CH:13]=[CH:14][c:15]2[cH:16][cH:17][c:18]([C:19](=[O:20])[O:21][CH2:22][CH3:23])[cH:24][cH:25]2)[CH2:10][CH2:11][CH2:12]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 73241636Tert-butyl 2-[2-(4-ethoxycarbonylphenyl)ethenyl]pyrrolidine-1-carboxylate

Product 1

HCID 73241624Ethyl 4-(2-pyrrolidin-2-ylethenyl)benzoate

Sources & evidence

ORD record
ord-4aec876c0b3f4bdd8f9a3aae10e52be4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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