Hydrochloric Acid → 3-methoxy-4-(4-methylpiperazin-1-ylmethyl)-N-{3-[4-(5-bromopyridin-3-yl)pyrimidin-2-ylamino]-4-methylphenyl}benzamide

HRID 2143302Notes

Reaction equation

HRID 2143302 reaction equation
[Br:1][c:2]1[cH:3][c:4](-[c:8]2[n:9][c:10]([NH:14][c:15]3[cH:16][c:17]([NH2:18])[cH:19][cH:20][c:21]3[CH3:22])[n:11][cH:12][cH:13]2)[cH:5][n:6][cH:7]1.[CH3:25][O:26][c:27]1[cH:28][c:29]([C:30](=[O:31])[Cl:32])[cH:33][cH:34][c:35]1[CH2:36][N:37]1[CH2:38][CH2:39][N:40]([CH3:43])[CH2:41][CH2:42]1.[ClH:23].[ClH:24]>>[Br:1][c:2]1[cH:3][c:4](-[c:8]2[n:9][c:10]([NH:14][c:15]3[cH:16][c:17]([NH:18][C:30]([c:29]4[cH:28][c:27]([O:26][CH3:25])[c:35]([CH2:36][N:37]5[CH2:38][CH2:39][N:40]([CH3:43])[CH2:41][CH2:42]5)[cH:34][cH:33]4)=[O:31])[cH:19][cH:20][c:21]3[CH3:22])[n:11][cH:12][cH:13]2)[cH:5][n:6][cH:7]1

Participants

4

Reactant 3

HCID 313Hydrochloric Acid2×HCID 230735153-Methoxy-4-[(4-methylpiperazin-1-yl)methyl]benzoyl chlorideHCID 23145966HCID 23145966, compound

Product 1

HCID 117867633-methoxy-4-(4-methylpiperazin-1-ylmethyl)-N-{3-[4-(5-bromopyridin-3-yl)pyrimidin-2-ylamino]-4-methylphenyl}benzamide

Sources & evidence

ORD record
ord-d27038246ebe402993cb7bd07d57e75b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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