Dichloromethane → 2-Hydroxy-3-trifluoromethyl-5-fluoro-7-bromo-2,3-dihydrobenzofuran

HRID 2143438Notes

Reaction equation

HRID 2143438 reaction equation
[Cl:55][CH2:56][Cl:57].[F:17][C:18]([CH:19]([CH:20]=[CH2:21])[c:22]1[c:23]([OH:30])[c:24]([Br:29])[cH:25][c:26]([F:28])[cH:27]1)([F:31])[F:32].[F:1][C:2]([F:3])([F:4])[CH:5]=[CH:7][CH2:8][O:6][c:9]1[cH:10][cH:11][c:12]([F:13])[cH:14][c:15]1[Br:16].[O-:33][O+:34]=[O:35].[c:36]1([P:37]([c:38]2[cH:39][cH:40][cH:41][cH:42][cH:43]2)[c:44]2[cH:45][cH:46][cH:47][cH:48][cH:49]2)[cH:50][cH:51][cH:52][cH:53][cH:54]1>>[OH:6][CH:20]1[CH:19]([C:18]([F:17])([F:31])[F:32])[c:22]2[c:23]([c:24]([Br:29])[cH:25][c:26]([F:28])[cH:27]2)[O:30]1

Participants

6

Reactant 5

HCID 6344DichloromethaneHCID 11776TriphenylphosphineHCID 24823OzoneHCID 221447402-(3-Trifluoromethylprop-1-en-3-yl)-4-fluoro-6-bromophenolHCID 539219781-(1-Trifluoromethylprop-1-en-3-yloxy)-2-bromo-4-fluorobenzene

Product 1

HCID 221448482-Hydroxy-3-trifluoromethyl-5-fluoro-7-bromo-2,3-dihydrobenzofuran

Sources & evidence

ORD record
ord-a95e02b3e6bd429583719ff424d24903
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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