Hydrogen Bromide → 6'-Chloro-2-fluoro-5-(4-piperidin-1-ylmethyl-phenyl)-[3,4]bipyridinyl-3'-ylamine
Reaction equation
[Br:1][c:2]1[cH:3][c:4](-[c:9]2[c:10]([NH2:16])[cH:11][n:12][c:13]([Cl:15])[cH:14]2)[c:5]([F:8])[n:6][cH:7]1.[BrH:17].[CH3:34][C:35]#[N:36].[F-:37].[K+:38].[N:18]1([CH2:24][c:25]2[cH:26][cH:27][c:28]([B:31]([OH:32])[OH:33])[cH:29][cH:30]2)[CH2:19][CH2:20][CH2:21][CH2:22][CH2:23]1.[OH2:39]>>[c:2]1(-[c:28]2[cH:27][cH:26][c:25]([CH2:24][N:18]3[CH2:19][CH2:20][CH2:21][CH2:22][CH2:23]3)[cH:30][cH:29]2)[cH:3][c:4](-[c:9]2[c:10]([NH2:16])[cH:11][n:12][c:13]([Cl:15])[cH:14]2)[c:5]([F:8])[n:6][cH:7]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-d637bcaa9a8b4cb69e0a9ed0aab712c8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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