Acetate → 4-(3-Bromo-furan-2-yl)-pyridine

HRID 2143692Notes

Reaction equation

HRID 2143692 reaction equation
[Br:1][c:2]1[o:3][cH:4][cH:5][c:6]1[Br:7].[C:17](=[O:18])([O-:19])[O-:20].[C:49]([O-:50])(=[O:51])[CH3:52].[C:54]([O-:55])(=[O:56])[CH3:57].[CH3:42][O:43][CH2:44][CH2:45][O:46][CH3:47].[K+:21].[K+:22].[OH2:48].[Pd+2:53].[c:23]1([P:24]([c:25]2[cH:26][cH:27][cH:28][cH:29][cH:30]2)[c:31]2[cH:32][cH:33][cH:34][cH:35][cH:36]2)[cH:37][cH:38][cH:39][cH:40][cH:41]1.[n:8]1[cH:9][cH:10][c:11]([B:14]([OH:15])[OH:16])[cH:12][cH:13]1>>[c:2]1(-[c:11]2[cH:10][cH:9][n:8][cH:13][cH:12]2)[o:3][cH:4][cH:5][c:6]1[Br:7]

Participants

10

Reactant 9

HCID 175Acetate2×HCID 813Potassium Cation2×HCID 962WaterHCID 80711,2-DimethoxyethaneHCID 11776TriphenylphosphineHCID 19660Carbonate IonHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 2734379(Pyridin-4-yl)boronic acidHCID 70215012,3-Dibromofuran

Product 1

HCID 157218314-(3-Bromo-furan-2-yl)-pyridine

Sources & evidence

ORD record
ord-9fee961b53654a8ba37e8ef2a2814962
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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